Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells
Background Thymic involution is a prominent characteristic of an aging immune system. When thymic function is reduced/absent, the peripheral T cell pool is subject to the laws of peripheral T cell homeostasis that favor survival/expansion of T cell receptors with relatively higher functional avidity...
| প্রধান লেখক: | , , , , , |
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| অন্যান্য লেখক: | |
| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
BioMed Central Ltd
2012
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| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/1721.1/70114 |