Using a structural and logics systems approach to infer bHLH–DNA binding specificity determinants

Using a structural and logics systems approach to infer bHLH–DNA binding specificity determinants

Numerous efforts are underway to determine gene regulatory networks that describe physical relationships between transcription factors (TFs) and their target DNA sequences. Members of paralogous TF families typically recognize similar DNA sequences. Knowledge of the molecular determinants of protein...

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Bibliographic Details
Main Authors: Masi, Federico De, Grove, Christian A., Vedenko, Anastasia, Alibes, Andreu, Gisselbrecht, Stephen S., Serrano, Luis, Walhout, Albertha J. M., Bulyk, Martha L.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Oxford University Press (OUP) 2012
Online Access:http://hdl.handle.net/1721.1/70992

Internet

http://hdl.handle.net/1721.1/70992

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