In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid–polymeric nanoparticles

Following recent successes with percutaneous coronary intervention (PCI) for treating coronary artery disease (CAD), many challenges remain. In particular, mechanical injury from the procedure results in extensive endothelial denudation, exposing the underlying collagen IV-rich basal lamina, which p...

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Bibliographic Details
Main Authors: Chan, Juliana Maria, Rhee, June-Wha, Drum, Chester L., Bronson, Roderick T., Golomb, Gershon, Farokhzad, Omid C., Langer, Robert S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences 2012
Online Access:http://hdl.handle.net/1721.1/71126
https://orcid.org/0000-0003-4255-0492