Compression and self-entanglement of single DNA molecules under uniform electric field

We experimentally study the effects of a uniform electric field on the conformation of single DNA molecules. We demonstrate that a moderate electric field (~200 V/cm) strongly compresses isolated DNA polymer coils into isotropic globules. Insight into the nature of these compressed states is gained...

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Bibliographic Details
Main Authors: Tang, Jing, Du, Ning, Doyle, Patrick S
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2012
Online Access:http://hdl.handle.net/1721.1/71148