Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells

Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells

Background The membrane cytoskeletal crosslinker, ezrin, a member of the ERM family of proteins, is frequently over-expressed in human breast cancers, and is required for motility and invasion of epithelial cells. Our group previously showed that ezrin acts co-operatively with the non-receptor tyros...

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Bibliographic Details
Main Authors: Mak, Hannah, Naba, Alexandra, Varma, Sonal, Schick, Colleen, Day, Andrew, SenGupta, Sandip K, Arpin, Monique, Elliott, Bruce E
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: BioMed Central Ltd. 2012
Online Access:http://hdl.handle.net/1721.1/71715

Internet

http://hdl.handle.net/1721.1/71715

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