Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction

The function of the essential checkpoint kinases Bub1 and BubR1 requires their recruitment to mitotic kinetochores. Kinetochore recruitment of Bub1 and BubR1 is proposed to rely on the interaction of the tetratricopeptide repeats (TPRs) of Bub1 and BubR1 with two KI motifs in the outer kinetochore p...

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Bibliographic Details
Main Authors: Krenn, Veronica, Wehenkel, Annemarie, Li, Xiaozheng, Santaguida, Stefano, Musacchio, Andrea
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Rockefeller University Press, The 2012
Online Access:http://hdl.handle.net/1721.1/71726
https://orcid.org/0000-0002-1501-6190