Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

Genome-scale engineering of living organisms requires precise and economical methods to efficiently modify many loci within chromosomes. One such example is the directed integration of chemically synthesized single-stranded deoxyribonucleic acid (oligonucleotides) into the chromosome of Escherichia...

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Bibliographic Details
Main Authors: Carr, Peter A., Sr., Wang, Harris H., Sterling, Bram Henry, Isaacs, Farren J., Lajoie, Marc J., Xu, George Jing, Church, George M., Jacobson, Joseph
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Oxford University Press (OUP) 2012
Online Access:http://hdl.handle.net/1721.1/71773
https://orcid.org/0000-0002-1332-3197
https://orcid.org/0000-0003-3222-0772

Internet

http://hdl.handle.net/1721.1/71773
https://orcid.org/0000-0002-1332-3197
https://orcid.org/0000-0003-3222-0772

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