Maintenance of tumor initiating cells of defined genetic composition by nucleostemin
Recent work has identified a subset of cells resident in tumors that exhibit properties similar to those found in normal stem cells. Such cells are highly tumorigenic and may be involved in resistance to treatment. However, the genes that regulate the tumor initiating cell (TIC) state are unknown. H...
Main Authors: | , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2012
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Online Access: | http://hdl.handle.net/1721.1/71896 |