Maintenance of tumor initiating cells of defined genetic composition by nucleostemin

Recent work has identified a subset of cells resident in tumors that exhibit properties similar to those found in normal stem cells. Such cells are highly tumorigenic and may be involved in resistance to treatment. However, the genes that regulate the tumor initiating cell (TIC) state are unknown. H...

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Bibliographic Details
Main Authors: Okamoto, Naoko, Yasukawa, Mami, Nguyen, Christine, Kasim, Vivi, Maida, Yoshiko, Possemato, Richard, Shibata, Tatsuhiro, Ligon, Keith L., Fukami, Kiyoko, Hahn, William C., Masutomi, Kenkichi
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: National Academy of Sciences 2012
Online Access:http://hdl.handle.net/1721.1/71896