Room Temperature Aryl Trifluoromethylation via Copper- Mediated Oxidative Cross-Coupling

A method for the room temperature copper-mediated trifluoromethylation of aryl and heteroaryl boronic acids has been developed. This protocol is amenable to normal benchtop setup and reactions typically require only 1−4 h. Proceeding under mild conditions, the method tolerates a range of functional...

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Bibliographic Details
Main Authors: Buchwald, Stephen Leffler, Senecal, Todd D., Parsons, Andrew
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/71959
https://orcid.org/0000-0003-3875-4775