Intermolecular Alignment in Beta 2-Microglobulin Amyloid Fibrils

The deposition of amyloid-like fibrils, composed primarily of the 99-residue protein β2-microglobulin (β2m), is one of the characteristic symptoms of dialysis-related amyloidosis. Fibrils formed in vitro at low pH and low salt concentration share many properties with the disease related fibrils and...

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Bibliographic Details
Main Authors: Debelouchina, Galia Tzvetanova, Bayro, Marvin J., Radford, Sheena E., Griffin, Robert Guy, Platt, Geoffrey W.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/72019
https://orcid.org/0000-0003-1589-832X