Systematic Single-Cell Analysis of Pichia pastoris Reveals Secretory Capacity Limits Productivity

Biopharmaceuticals represent the fastest growing sector of the global pharmaceutical industry. Cost-efficient production of these biologic drugs requires a robust host organism for generating high titers of protein during fermentation. Understanding key cellular processes that limit protein producti...

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Bibliografski detalji
Glavni autori: Politano, Timothy James, Panagiotou, Vasiliki, Stadheim, Terrance A., Love, Kerry R., Jiang, Bo, S.M. Massachusetts Institute of Technology, Love, John C
Daljnji autori: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Članak
Jezik:en_US
Izdano: Public Library of Science 2012
Online pristup:http://hdl.handle.net/1721.1/72414
https://orcid.org/0000-0003-0921-3144