Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

Most metazoan microRNA (miRNA) target sites have perfect pairing to the seed region, located near the miRNA 5′ end. Although pairing to the 3′ region sometimes supplements seed matches or compensates for mismatches, pairing to the central region has been known to function only at rare sites that imp...

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Bibliographic Details
Main Authors: Shin, Chanseok, Nam, Jin-Wu, Farh, Kyle Kai-How, Chiang, H. Rosaria, Shkumatava, Alena, Bartel, David
Other Authors: move to dc.description.sponsorship
Format: Article
Language:en_US
Published: Elsevier 2012
Online Access:http://hdl.handle.net/1721.1/72450
https://orcid.org/0000-0002-3872-2856