Widespread shortening of 3′UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
In cancer cells, genetic alterations can activate proto-oncogenes, thereby contributing to tumorigenesis. However, the protein products of oncogenes are sometimes overexpressed without alteration of the proto-oncogene. Helping to explain this phenomenon, we found that when compared to similarly prol...
| Hlavní autoři: | , |
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| Další autoři: | |
| Médium: | Článek |
| Jazyk: | en_US |
| Vydáno: |
Elsevier
2012
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| On-line přístup: | http://hdl.handle.net/1721.1/72464 https://orcid.org/0000-0002-3872-2856 |