Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination

Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination

The ability to induce humoral and cellular immunity via antigen delivery through the unbroken skin (epicutaneous immunization, EPI) has immediate relevance for vaccine development. However, it is unclear which adjuvants induce protective memory CD8 T-cell responses by this route, and the molecular a...

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Bibliographic Details
Main Authors: Olvera-Gomez, Irlanda, Hamilton, Sara E., Xiao, Zhengguo, Guimaraes, Carla P., Ploegh, Hidde, Hogquist, Kristin A., Wang, Liangchun, Jameson, Stephen C.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences 2012
Online Access:http://hdl.handle.net/1721.1/72523
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/72523
https://orcid.org/0000-0002-1090-6071

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