Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination
The ability to induce humoral and cellular immunity via antigen delivery through the unbroken skin (epicutaneous immunization, EPI) has immediate relevance for vaccine development. However, it is unclear which adjuvants induce protective memory CD8 T-cell responses by this route, and the molecular a...
Main Authors: | Olvera-Gomez, Irlanda, Hamilton, Sara E., Xiao, Zhengguo, Guimaraes, Carla P., Ploegh, Hidde, Hogquist, Kristin A., Wang, Liangchun, Jameson, Stephen C. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2012
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Online Access: | http://hdl.handle.net/1721.1/72523 https://orcid.org/0000-0002-1090-6071 |
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