Biased chromatin signatures around polyadenylation sites and exons

Biased chromatin signatures around polyadenylation sites and exons

Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between chromatin structure and pre-mRNA processing is poorly understood. We observed strong nucleosome depletion around human polyadenylation sites (PAS) and nucleosome enrichmen...

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Bibliographic Details
Main Authors: Nielsen, Cydney B., Padgett, Richard A., Spies, Noah, Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2012
Online Access:http://hdl.handle.net/1721.1/72553

Internet

http://hdl.handle.net/1721.1/72553

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