c-Myc regulates transcriptional pause release

Recruitment of the RNA polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA-binding transcription factors is well recognized as a key regulatory step in gene expression. We report here that promoter-proximal pausing is a general feature of transcription by Pol II in...

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Bibliographic Details
Main Authors: Rahl, Peter B., Lin, Charles Y., Flynn, Ryan A., McCuine, Scott, Sharp, Phillip A., Young, Richard A., White, Amy C., Burge, Christopher B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2012
Online Access:http://hdl.handle.net/1721.1/72558
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0001-5013-0442
https://orcid.org/0000-0001-8855-8647