PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions

Motivation: As high-throughput transcriptome sequencing provides evidence for novel transcripts in many species, there is a renewed need for accurate methods to classify small genomic regions as protein coding or non-coding. We present PhyloCSF, a novel comparative genomics method that analyzes a mu...

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Bibliographic Details
Main Authors: Lin, Michael F., Jungreis, Irwin, Kellis, Manolis
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/1721.1/72566