Activation of tolerogenic dendritic cells in the tumor draining lymph CD8+ T cells engineered to express CD40 ligand
Tolerogenic dendritic cells in the tumor microenvironment can inhibit the generation and maintenance of robust antitumor T cell responses. In this study, we investigated the effects of local delivery of CD40L by tumor-reactive CD8[supersript +] T cells on dendritic cell activation and antitumor T ce...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
The American Association of Immunologists
2012
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| Online Access: | http://hdl.handle.net/1721.1/72611 https://orcid.org/0000-0003-2398-5896 https://orcid.org/0000-0002-5687-6154 |