Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential

Mesenchymal stem cells secreting angiopoietin-like-5 support efficient expansion of human hematopoietic stem cells without compromising their repopulating potential

Clinical and preclinical applications of human hematopoietic stem cells (HSCs) are often limited by scarcity of cells. Expanding human HSCs to increase their numbers while maintaining their stem cell properties has therefore become an important area of research. Here, we report a robust HSC cocultur...

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Bibliographic Details
Main Authors: Drake, Adam, Chen, Qingfeng, Dong, Di, Leskov, Ilya B., Fragoso, Maria F., Li, Yan, Iliopoulou, Bettina P., Hwang, William, Lodish, Harvey F., Chen, Jianzhu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Mary Ann Liebert 2012
Online Access:http://hdl.handle.net/1721.1/72658
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-5687-6154

Internet

http://hdl.handle.net/1721.1/72658
https://orcid.org/0000-0002-7029-7415
https://orcid.org/0000-0002-5687-6154

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