Engineering transcription factors with novel DNA-binding specificity using comparative genomics
The transcriptional program for a gene consists of the promoter necessary for recruiting RNA polymerase along with neighboring operator sites that bind different activators and repressors. From a synthetic biology perspective, if the DNA-binding specificity of these proteins can be changed, then the...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Oxford University Press
2012
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| Online Access: | http://hdl.handle.net/1721.1/73031 https://orcid.org/0000-0001-8294-9364 |