Spatial effects on the speed and reliability of protein–DNA search
Strong experimental and theoretical evidence shows that transcription factors (TFs) and other specific DNA-binding proteins find their sites using a two-mode search: alternating between three-dimensional (3D) diffusion through the cell and one-dimensional (1D) sliding along the DNA. We show that, du...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Oxford University Press (OUP)
2012
|
| Online Access: | http://hdl.handle.net/1721.1/73060 https://orcid.org/0000-0002-0785-5410 |