Overexpression of CREB in the Nucleus Accumbens Shell Increases Cocaine Reinforcement in Self-Administering Rats

Overexpression of CREB in the Nucleus Accumbens Shell Increases Cocaine Reinforcement in Self-Administering Rats

Chronic exposure to addictive drugs enhances cAMP response element binding protein (CREB)-regulated gene expression in nucleus accumbens (NAc), and these effects are thought to reduce the positive hedonic effects of passive cocaine administration. Here, we used viral-mediated gene transfer to produc...

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Bibliographic Details
Main Authors: Larson, Erin B., Graham, Danielle L., Arzaga, Rose R., Buzin, Nicole, Webb, Joseph, Green, Thomas A., Bass, Caroline E., Neve, Rachael L., Terwilliger, Ernest F., Nestler, Eric J., Self, David W.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2012
Online Access:http://hdl.handle.net/1721.1/73068
https://orcid.org/0000-0002-3854-5968

Internet

http://hdl.handle.net/1721.1/73068
https://orcid.org/0000-0002-3854-5968

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