Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F2CTP: covalent modification
Ribonucleotide reductase (RNR) from Lactobacillus leichmannii, a 76 kDa monomer using adenosylcobalamin (AdoCbl) as a cofactor, catalyzes the conversion of nucleoside triphosphates to deoxynucleotides and is rapidly (<30 s) inactivated by 1 equiv of 2′,2′-difluoro-2′-deoxycytidine 5′-triphosphate...
| Главные авторы: | , |
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| Другие авторы: | |
| Формат: | Статья |
| Язык: | en_US |
| Опубликовано: |
American Chemical Society (ACS)
2012
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| Online-ссылка: | http://hdl.handle.net/1721.1/73105 https://orcid.org/0000-0001-8076-4489 |