Enhancing Protease Activity Assay in Droplet-Based Microfluidics Using a Biomolecule Concentrator

Enhancing Protease Activity Assay in Droplet-Based Microfluidics Using a Biomolecule Concentrator

We introduce an integrated microfluidic device consisting of a biomolecule concentrator and a microdroplet generator, which enhances the limited sensitivity of low-abundance enzyme assays by concentrating biomolecules before encapsulating them into droplet microreactors. We used this platform to det...

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Bibliographic Details
Main Authors: Chen, Chia-Hung, Sarkar, Aniruddh, Song, Yong-Ak, Miller, Miles Aaron, Kim, Sung Jae, Griffith, Linda G., Lauffenburger, Douglas A., Han, Jongyoon
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/73163
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0001-7215-1439

Internet

http://hdl.handle.net/1721.1/73163
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0001-7215-1439

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