Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor

Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor

A high-throughput screen of the NIH-MLSMR compound collection, along with a series of secondary assays to identify potential targets of hit compounds, previously identified a 1,3-diaminobenzene scaffold that targets protease-activated receptor 1 (PAR1). We now report additional structure–activity re...

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Xehetasun bibliografikoak
Egile Nagusiak: Schreiber, Stuart L., Dockendorff, Chris, Aisiku, Omozuanvbo, VerPlank, Lynn, Dilks, James R., Smith, Daniel A., Gunnink, Susanna F., Dowal, Louisa, Negri, Joseph, Palmer, Michelle, MacPherson, Lawrence, Flaumenhaft, Robert
Beste egile batzuk: Howard Hughes Medical Institute
Formatua: Artikulua
Hizkuntza:en_US
Argitaratua: American Chemical Society (ACS) 2012
Sarrera elektronikoa:http://hdl.handle.net/1721.1/73170

Internet

http://hdl.handle.net/1721.1/73170

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