Predicting the binding preference of transcription factors to individual DNA k-mers
Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly characterized, in part due to the difficulty associated with determining their specificity experimentally...
Principais autores: | , , , , , , , , , |
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Outros Autores: | |
Formato: | Artigo |
Idioma: | en_US |
Publicado em: |
Oxford University Press (OUP)
2012
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Acesso em linha: | http://hdl.handle.net/1721.1/73182 |