Predicting the binding preference of transcription factors to individual DNA k-mers
Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly characterized, in part due to the difficulty associated with determining their specificity experimentally...
Main Authors: | Bulyk, Martha L., Philippakis, Anthony A., Alleyne, Trevis M., Peña-Castillo, Lourdes, Badis, Gwenael, Talukder, Shaheynoor, Berger, Michael F., Gehrke, Andrew R., Morris, Quaid D., Hughes, Timothy R. |
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Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press (OUP)
2012
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Online Access: | http://hdl.handle.net/1721.1/73182 |
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