Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Gene duplication is a powerful driver of evolution. Newly duplicated genes acquire new roles that are relevant to fitness, or they will be lost over time. A potential path to functional relevance is mutation of the coding sequence leading to the acquisition of novel biochemical properties, as analyz...

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Автори: Bochkis, Irina M., Schug, Jonathan, Ye, Diana Z., Kurinna, Svitlana, Stratton, Sabrina A., Barton, Michelle C., Kaestner, Klaus H.
Формат: Стаття
Мова:en_US
Опубліковано: Public Library of Science 2012
Онлайн доступ:http://hdl.handle.net/1721.1/73529