Zebrafish Hagoromo mutants upregulate fgf8 post-embryonically and develop neuroblastoma

We screened an existing collection of zebrafish insertional mutants for cancer susceptibility by histologic examination of heterozygotes at 2 years of age. As most mutants had no altered cancer predisposition, this provided the first comprehensive description of spontaneous tumor spectrum and freque...

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Bibliographic Details
Main Authors: Amsterdam, Adam, Lai, Kevin, Komisarczuk, Anna Z., Becker, Thomas S., Bronson, Roderick T., Hopkins, Nancy H., Lees, Jacqueline
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for Cancer Research 2012
Online Access:http://hdl.handle.net/1721.1/73548
https://orcid.org/0000-0001-9451-2194
https://orcid.org/0000-0001-9804-536X