A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancers

Abstract Background Understanding the fundamental mechanisms of tumorigenesis remains one of the most pressing problems in modern biology. To this end, stem-like cells with tumor-initiating potential have become a central focus in cancer research. While the cancer stem cell hypothesis presents a com...

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Bibliographic Details
Main Authors: Berger, Bonnie, Palmer, Nathan Patrick, Schmid, Patrick Raphael, Kohane, Isaac
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central Ltd 2012
Online Access:http://hdl.handle.net/1721.1/73622
https://orcid.org/0000-0002-2724-7228