Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells

Pyriplatin, cis-diammine(pyridine)chloroplatinum(II), a platinum-based antitumor drug candidate, is a cationic compound with anticancer properties in mice and is a substrate for organic cation transporters that facilitate oxaliplatin uptake. Unlike cisplatin and oxaliplatin, which form DNA cross-lin...

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Bibliographic Details
Main Authors: Lovejoy, Katherine S., Lippard, Stephen J., Serova, Maria, Bieche, Ivan, Emami, Shahin, D’Incalci, Maurizio, Broggini, Massimo, Erba, Eugenio, Gespach, Christian, Cvitkovic, Esteban, Faivre, Sandrine, Raymond, Eric
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Association for Cancer Research 2012
Online Access:http://hdl.handle.net/1721.1/74056
https://orcid.org/0000-0002-2693-4982