The Radical Use of Rossmann and TIM Barrel Architectures for Controlling Coenzyme B[subscript 12] Chemistry
The ability of enzymes to harness free-radical chemistry allows for some of the most amazing transformations in nature, including reduction of ribonucleotides and carbon skeleton rearrangements. Enzyme cofactors involved in this chemistry can be large and complex, such as adenosylcobalamin (coenzyme...
Main Authors: | , , |
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Format: | Article |
Language: | en_US |
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Annual Reviews
2012
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Online Access: | http://hdl.handle.net/1721.1/74068 https://orcid.org/0000-0001-5486-2755 |