Optical Trapping with High Forces Reveals Unexpected Behaviors of Prion Fibrils
Amyloid fibrils are important in diverse cellular functions, feature in many human diseases and have potential applications in nanotechnology. Here we describe methods that combine optical trapping and fluorescent imaging to characterize the forces that govern the integrity of amyloid fibrils formed...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Nature Publishing Group
2012
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| Online Access: | http://hdl.handle.net/1721.1/74086 https://orcid.org/0000-0002-4614-251X https://orcid.org/0000-0003-1307-882X https://orcid.org/0000-0002-2193-377X |