High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

Heat-shock factor 1 (HSF1) is the master transcriptional regulator of the cellular response to heat and a wide variety of other stressors. We previously reported that HSF1 promotes the survival and proliferation of malignant cells. At this time, however, the clinical and prognostic significance of H...

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Bibliographic Details
Main Authors: Santagata, Sandro, Mendillo, Marc L., Whitesell, Luke, Lindquist, Susan, Hu, Rong, Lin, Nancy U., Collins, Laura C., Hankinson, Susan E., Schnitt, Stuart J., Tamimi, Rulla M., Ince, Tan A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences 2012
Online Access:http://hdl.handle.net/1721.1/74089
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/74089
https://orcid.org/0000-0003-1307-882X

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