Rapid dissection and model-based optimization of inducible enhancers in human cells using a massively parallel reporter assay
Learning to read and write the transcriptional regulatory code is of central importance to progress in genetic analysis and engineering. Here we describe a massively parallel reporter assay (MPRA) that facilitates the systematic dissection of transcriptional regulatory elements. In MPRA, microarray-...
Main Authors: | , , , , , , , , , , , , |
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Outros Autores: | |
Formato: | Artigo |
Idioma: | en_US |
Publicado em: |
Nature Publishing Group
2012
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Acesso em linha: | http://hdl.handle.net/1721.1/74097 https://orcid.org/0000-0002-0964-0616 |