Rapid dissection and model-based optimization of inducible enhancers in human cells using a massively parallel reporter assay
Learning to read and write the transcriptional regulatory code is of central importance to progress in genetic analysis and engineering. Here we describe a massively parallel reporter assay (MPRA) that facilitates the systematic dissection of transcriptional regulatory elements. In MPRA, microarray-...
Main Authors: | , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2012
|
Online Access: | http://hdl.handle.net/1721.1/74097 https://orcid.org/0000-0002-0964-0616 |