Developmental control of gene copy number by repression of replication initiation and fork progression

Developmental control of gene copy number by repression of replication initiation and fork progression

Precise DNA replication is crucial for genome maintenance, yet this process has been inherently difficult to study on a genome-wide level in untransformed differentiated metazoan cells. To determine how metazoan DNA replication can be repressed, we examined regions selectively under-replicated in Dr...

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Bibliographic Details
Main Authors: Sher, Noa, Bell, George W., Li, Sharon, Nordman, Jared T., Eng, Thomas, Eaton, Matthew Lucas, MacAlpine, David M., Orr-Weaver, Terry L.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2012
Online Access:http://hdl.handle.net/1721.1/74257
https://orcid.org/0000-0002-8305-9125
https://orcid.org/0000-0002-7934-111X

Internet

http://hdl.handle.net/1721.1/74257
https://orcid.org/0000-0002-8305-9125
https://orcid.org/0000-0002-7934-111X

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