XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells
XBP-1, a transcription factor that drives the unfolded protein response (UPR), is activated in B cells when they differentiate to plasma cells. Here, we show that in the B cells, whose capacity to secrete IgM has been eliminated, XBP-1 is induced normally on induction of differentiation, suggesting...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2012
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Online Access: | http://hdl.handle.net/1721.1/74263 https://orcid.org/0000-0003-0921-3144 https://orcid.org/0000-0002-1090-6071 |