The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc

The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc

Angelman Syndrome is a debilitating neurological disorder caused by mutation of the E3 ubiquitin ligase Ube3A, a gene whose mutation has also recently been associated with autism spectrum disorders (ASDs). The function of Ube3A during nervous system development and how Ube3A mutations give rise to c...

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Bibliographic Details
Main Authors: Ploegh, Hidde, Maehr, Rene, Greer, Paul L., Hanayama, Rikinari, Bloodgood, Brenda L., Mardinly, Alan R., Lipton, David M., Flavell, Steven W., Kim, Tae-Kyung, Griffith, Eric C., Waldon, Zachary, Chowdhury, Shoaib, Worley, Paul F., Steen, Judith, Greenberg, Michael E.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2012
Online Access:http://hdl.handle.net/1721.1/74264
https://orcid.org/0000-0002-1090-6071

Internet

http://hdl.handle.net/1721.1/74264
https://orcid.org/0000-0002-1090-6071

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