A unique regulatory phase of DNA methylation in the early mammalian embryo

A unique regulatory phase of DNA methylation in the early mammalian embryo

DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization, followed by passive loss that reaches a minimum at the blastocyst stage. However, this model is based on limited data, and so f...

Full description

Bibliographic Details
Main Authors: Chan, Michelle Mei Wah, Regev, Aviv, Smith, Zachary D., Gu, Hongcang, Gnirke, Andreas, Meissner, Alexander, Mikkelsen, Tarjei Sigurd, 1978-
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:en_US
Published: Nature Publishing Group 2012
Online Access:http://hdl.handle.net/1721.1/74536
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/74536
https://orcid.org/0000-0001-8567-2049

Similar Items