A unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization, followed by passive loss that reaches a minimum at the blastocyst stage. However, this model is based on limited data, and so f...
| Hauptverfasser: | , , , , , , |
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| Format: | Artikel |
| Sprache: | en_US |
| Veröffentlicht: |
Nature Publishing Group
2012
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| Online Zugang: | http://hdl.handle.net/1721.1/74536 https://orcid.org/0000-0001-8567-2049 |