mTOR and cancer: many loops in one pathway

The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division that responds to a variety of stimuli, including nutrient, energy, and growth factors. In the last years, a significant number of pieces have been added to the puzzle of how mTOR coordinates and executes its f...

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Bibliographic Details
Main Authors: Efeyan, Alejo, Sabatini, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2012
Online Access:http://hdl.handle.net/1721.1/74543
https://orcid.org/0000-0002-1446-7256