Intermolecular Structure Determination of Amyloid Fibrils with 2 Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

Intermolecular Structure Determination of Amyloid Fibrils with 2 Magic-Angle Spinning and Dynamic Nuclear Polarization NMR

We describe magic-angle spinning NMR experiments designed to elucidate the interstrand architecture of amyloid fibrils. Three methods are introduced for this purpose, two being based on the analysis of long-range [superscript 13]C–[superscript 13]C correlation spectra and the third based on the iden...

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Bibliographic Details
Main Authors: Bayro, Marvin J., Debelouchina, Galia Tzvetanova, Eddy, Matthew Thomas, Birkett, Neil R., MacPhee, Catherine E., Rosay, Melanie, Maas, Werner, Dobson, Christopher M., Griffin, Robert Guy
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/74559
https://orcid.org/0000-0002-3349-6212
https://orcid.org/0000-0003-1589-832X

Internet

http://hdl.handle.net/1721.1/74559
https://orcid.org/0000-0002-3349-6212
https://orcid.org/0000-0003-1589-832X

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