Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling
Bring your own copper: Copper-chelating azides undergo much faster click reactions (CuAAC) than nonchelating azides under a variety of biocompatible conditions. This kinetic enhancement allows site-specific protein labeling to be performed on the surface of living cells with only 10–40 μM Cu[supersc...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Wiley Blackwell
2012
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| Online Access: | http://hdl.handle.net/1721.1/74563 https://orcid.org/0000-0002-8277-5226 |