Tuning Genetic Clocks Employing DNA Binding Sites

Periodic oscillations play a key role in cell physiology from the cell cycle to circadian clocks. The interplay of positive and negative feedback loops among genes and proteins is ubiquitous in these networks. Often, delays in a negative feedback loop and/or degradation rates are a crucial mechanism...

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Bibliographic Details
Main Authors: Del Vecchio, Domitilla, Jayanthi, Shridhar
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/1721.1/74639
https://orcid.org/0000-0001-6472-8576