Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells
Under the instruction of cell-fate–determining, DNA-binding transcription factors, chromatin-modifying enzymes mediate and maintain cell states throughout development in multicellular organisms. Currently, small molecules modulating the activity of several classes of chromatin-modifying enzymes are...
Main Authors: | , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2012
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Online Access: | http://hdl.handle.net/1721.1/74656 |