Mena binds α5 integrin directly and modulates α5β1 function

Mena binds α5 integrin directly and modulates α5β1 function

Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell–cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within these structures. We find that Mena forms an adhesion-regulated complex with α5β...

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Bibliographic Details
Main Authors: Gupton, Stephanie L., Riquelme, Daisy Noelia, Hughes-Alford, Shannon Kay, Tadros, Jenny, Rudina, Shireen S., Hynes, Richard O., Lauffenburger, Douglas A., Gertler, Frank
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Rockefeller University Press, The 2012
Online Access:http://hdl.handle.net/1721.1/74675
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0002-3048-7927
https://orcid.org/0000-0001-7603-8396

Internet

http://hdl.handle.net/1721.1/74675
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0002-3048-7927
https://orcid.org/0000-0001-7603-8396

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