A global sampling approach to designing and reengineering RNA secondary structures

The development of algorithms for designing artificial RNA sequences that fold into specific secondary structures has many potential biomedical and synthetic biology applications. To date, this problem remains computationally difficult, and current strategies to address it resort to heuristics and s...

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Bibliographic Details
Main Authors: Levin, Alexander, Lis, Mieszko, Ponty, Yann, O'Donnell, Charles William, Devadas, Srinivas, Berger, Bonnie, Waldispuhl, Jerome
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/1721.1/74681
https://orcid.org/0000-0001-8253-7714
https://orcid.org/0000-0002-2724-7228