A global sampling approach to designing and reengineering RNA secondary structures
The development of algorithms for designing artificial RNA sequences that fold into specific secondary structures has many potential biomedical and synthetic biology applications. To date, this problem remains computationally difficult, and current strategies to address it resort to heuristics and s...
Main Authors: | Levin, Alexander, Lis, Mieszko, Ponty, Yann, O'Donnell, Charles William, Devadas, Srinivas, Berger, Bonnie, Waldispuhl, Jerome |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press
2012
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Online Access: | http://hdl.handle.net/1721.1/74681 https://orcid.org/0000-0001-8253-7714 https://orcid.org/0000-0002-2724-7228 |
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