Differential effects of insulin signaling on individual carbon fluxes for fatty acid synthesis in brown adipocytes

Considering the major role of insulin signaling on fatty acid synthesis via stimulation of lipogenic enzymes, differential effects of insulin signaling on individual carbon fluxes for fatty acid synthesis have been investigated by comparing the individual lipogenic fluxes in WT and IRS-1 knockout (I...

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Bibliographic Details
Main Authors: Yoo, Hyuntae, Antoniewicz, Maciek, Kelleher, Joanne K., Stephanopoulos, Gregory
Format: Article
Language:English
Published: 2004
Subjects:
Online Access:http://hdl.handle.net/1721.1/7478