Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

Nanoparticle (NP) drug delivery systems (5−250 nm) have the potential to improve current disease therapies because of their ability to overcome multiple biological barriers and releasing a therapeutic load in the optimal dosage range. Rapid clearance of circulating nanoparticles during systemic deli...

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Bibliographic Details
Main Authors: Alexis, Frank, Molnar, Linda K., Farokhzad, Omid C., Pridgen, Eric M.
Other Authors: MIT-Harvard Center for Cancer Nanotechnology Excellence
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/75024
https://orcid.org/0000-0002-2640-3006